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“School of Nano-Sciences”

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Paper   IPM / Nano-Sciences / 16169
School of Nano Science
  Title:   Colorimetric microfluidic paper-based sensor for determination of nitrite in drinking water with enhanced color development
  Author(s): 
1.  Mansoor Arvand
2.  Nima Arjmandi
3.  Mehdi Shakibaie
4.  Somayeh Jafarinejad
5.  Reza Shahghadami
6.  Pezhman Sasanpour
  Status:   Published
  Journal: J. Phys. D: Appl. Phys.
  Vol.:  53
  Year:  2020
  Pages:   355403
  Publisher(s):   IOP Publishing Ltd
  Supported by:  IPM
  Abstract:
A low cost colorimetric microfluidic paper-based analytical device (µPAD) for the determination of nitrite in real samples with improved precision has been fabricated and its performance has been evaluated. The miuPAD was fabricated by laser cutting and patterning on the paper and the nitrite concentration measurement is based on the modified Griess assay. In this assay, tartaric acid was used as an antioxidant reagent to increase Griess reagent stability. A novel geometrical design was used to achieve better color gradient over miuPAD detection zone for improving the precision of the measurements. The results of measurement indicate that the fabricated device could successfully detect and quantify the nitrite concentration in real samples with the limit of detection of 15 µM. The results are in good accordance with the results of spectrophotometry. The fabricated sensor has the potential to be applied for monitoring of the trace level of nitrite in drinking water and environmental applications.

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