IPM Calendar 
Monday 29 April 2024   Today  
Events for day: Thursday 25 April 2019    
           10:00 - 11:00     Weekly Seminar
Systematic identification of cell type specific broad chromatin domain and their transitions from stem to mature cells

School
BIOLOGICAL SCIENCES

Post-translational modifications to histone tails define focal (few hundreds basepairs) chromatin states discriminating genomics features, such as cis-regulatory elements and transcribed regions, across development. These focal states can cluster to partition the genome into broad chromatin domains, such as Large Organized Chromatin Lysine modifications (LOCKs) and Cluster Of cis-Regulatory Elements (COREs). Ali Madani developed Clustering of genomic REgions Analysis Method (CREAM) to systematically study these broad chromatin domains in each cell type. In this talk, he is going to discuss about utility of his tool in studying cis-regulatory ...