IPM Calendar 
Wednesday 21 March 2018   Today  
Events for day: Thursday 14 September 2017    
           10:00 - 11:00     Special Seminar
The effect of randomness on the fate of mutants: Minority rules


Abstract: In this research, we study the effect of spatial randomness on
the chances of mutant fixation in a population of individuals of a constant
Such problems arise in models of cancer initiation and progression,
bacterial dynamics, and drug resistance. It turns out that spatial
heterogeneity rede fines the notion of neutrality,
allowing, e.g., a minority of cells (whose fitness values are drawn from
the same distribution as that of the wild type) to behave as if they had a
selective advantage. The effect can be very significant (increasing the
probability of mutant inva ...