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“School of Particles And Accelerator”

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Paper   IPM / Particles And Accelerator / 16013
School of Particles and Accelerator
  Title:   Dose Frequency Analysis of the DNA Surviving Fraction In a Pulsed Plasma Facility
  Author(s):  Mahmud Vahdat Roshan
  Status:   Submitted
  Journal: Journal of Biological Physics
  Year:  2020
  Supported by:  IPM
  Abstract:
Schemed with high repetition rate, the plasma focus device promises to simulate the radiation environment and analyze the biological effects on cells. The NX2 plasma focus is the lowest energy device for which intense high energy radiation beams have been observed. The most radiation-sensitive site within the cell, DNA, is irradiated by 110 j proton beams at high operation frequency. The PF device operated at 1 Hz repetition rate produces ten Double-Strand breaks, DSB, per second. The surviving fraction of the DNA is likely to be more affected by higher dose frequencies.

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