• 1
  • 2
  • 5
  • 6
  • 7
  • 8
  • 9
  • 3
  • 4
IPM
30
YEARS OLD

“School of Biological”

Back to Papers Home
Back to Papers of School of Biological

Paper   IPM / Biological / 15126
School of Biological Sciences
  Title:   DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism
  Author(s): 
1 . Ali Sharifi-Zarchi
2 . Daniela Gerovska
3 . Kenjiro Adachi
4 . Mehdi Totonchi
5 . Hamid Pezeshk
6 . Ryan Taft
7 . Hans Schöler
8 . Hamidreza Chitsaz
9 . Mehdi Sadeghi
10 . Hossein Baharvand
11 . Marcos Araúzo-Bravo
  Status:   Published
  Journal: BMC Genomics
  No.:  1
  Vol.:  18
  Year:  2017
  Pages:   964
  Supported by:  IPM
  Abstract:
DNA methylation at promoters is largely correlated with inhibition of gene expression. However, the role of DNA methylation at enhancers is not fully understood, although a crosstalk with chromatin marks is expected. Actually, there exist contradictory reports about positive and negative correlations between DNA methylation and H3K4me1, a chromatin hallmark of enhancers.

Download TeX format
back to top
Clients Logo
Clients Logo
Clients Logo
Clients Logo
Clients Logo
Clients Logo
Clients Logo
Clients Logo
scroll left or right