• 1
  • 2
  • 5
  • 6
  • 7
  • 8
  • 9
  • 3
  • 4
IPM
30
YEARS OLD

“School of Physics”

Back to Papers Home
Back to Papers of School of Physics

Paper   IPM / P / 15069
School of Physics
  Title:   Application of new ZnO nanoformulation and Ag/Fe/ZnO nanocomposites as water-based nanofluids to consider in vitro cytotoxic effects against MCF-7 breast cance...
  Author(s): 
1 . M.H. Abdolmohammadi
2 . F. Fallahian
3 . Z. Fakhroueian
4 . M. Kamalian
5 . P. Keyhanvar
6 . F. M. Harsini
7 . A. Shafiekhani
  Status:   Published
  Journal: Artificial Cells, Nanomedicine, and Biotechnology
  Vol.:  45
  Year:  2017
  Pages:   1-9
  Supported by:  IPM
  Abstract:
Novel formulations of nanocomposites derived from ZnO nanoparticles have provided potential biomedical applications as a new strategy for treatment of breast cancer. In this research, two types of ZnO nanomaterials were synthesized by sol–gel hydrothermal process and co-precipitation containing fast quenching and also surface modification methods. The cytotoxic effects on growth of the breast cancer cell lines MCF-7 were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Cell viability of the breast cancer cell line MCF-7 was reduced with increasing ZnO nanofluid concentrations at 48 and 72 h of treatment. The IC50 value of MCF-7 cells after 72 h of treatment with the first product ZnO (a) and second one ZnO (c) were measured as 51.02 and 48.63 μg/ml, respectively (P < 0.05).

Download TeX format
back to top
Clients Logo
Clients Logo
Clients Logo
Clients Logo
Clients Logo
Clients Logo
Clients Logo
Clients Logo
scroll left or right