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IPM
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“School of Biological”

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Paper   IPM / Biological / 13238
School of Biological Sciences
  Title:   STON: Anovel method for protein three-dimensional structure comparison
  Author(s): 
1 . C. Eslahchi.
2 . H. Pezeshk.
3 . M. Sadeghi.
4 . A. M. Rahimi.
5 . H. Maboudi Afkham.
6 . S. Arab.
  Status:   Published
  Journal: Computers in Biology and Medicine
  No.:  2
  Vol.:  39
  Year:  2009
  Pages:   166-172
  Supported by:  IPM
  Abstract:
Protein structure comparison is an important problem in bioinformatics and has many applications in the study of structural and functional genomics. During the last decades, various heuristic methods have been developed to solve the protein structure comparison problem. Most of the protein structure comparison methods give the alignment based on the minimum RMSD (root mean square deviation) and ignore many significant local alignments that may be important for evolutional or functional studies. We have developed a new algorithm to find aligned residues in two proteins with desired RMSD value. The parameterized distance and rotation in this program enable us to search for strongly or weakly similar aligned fragments in two proteins. More info: http://www.bioinf.cs.ipm.ir/softwares/ston/

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