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IPM
30
YEARS OLD

“School of Biological Sciences”

Paper   IPM / Biological Sciences / 13203
   School of Biological Sciences
  Title: A New Protein Domain Assignment Algorithm
  Author(s):
1 . C. Eslahchi.
2 . E. S. Ansari.
  Status: Published
  Journal: Communications in Mathematical and Computer Chemistry
  Vol.: 71
  Year: 2014
  Pages: 445-456
  Supported by: IPM
  Abstract:
Assignment of structural domains in complex protein structures is an important task in bioinformatics researches. As the number of known protein structures grows rapidly, the need for automatic methods for determining protein domains based on the proteins tree-dimensional structure becomes more desirable. In this paper, we introduce a new domain decomposition algorithm which is based on the dominating set of the graph representation of a protein. To evaluate our method, we compare our results with the other computational methods on a commonly used benchmark of 55 proteins. It is shown that the performance of our algorithm is better than the other automatic methods

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