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IPM
30
YEARS OLD

“School of Biological Sciences”

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Paper   IPM / Biological Sciences / 13159
School of Biological Sciences
  Title:   A new graph-based method for global alignment of protein-protein interaction networks
  Author(s): 
1.  B. Neyshabur.
2.  A. Khadem.
3.  S. Hashemifar.
4.  S. Arab.
  Status:   Published
  Journal: Bioinformatics
  No.:  13
  Vol.:  29
  Year:  2013
  Pages:   1654-1662
  Supported by:  IPM
  Abstract:
The interactions among proteins and the resulting networks of such interactions have a central role in cell biology. Aligning these networks gives us important information, such as conserved complexes and evolutionary relationships. Although there have been several publications on the global alignment of protein networks; however, none of proposed methods are able to produce a highly conserved and meaningful alignment. Moreover, time complexity of current algorithms makes them impossible to use for multiple alignment of several large networks together.

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